2024 年 – 第 2 页 – 清华大学田博学课题组

12 篇文章

Journal of Chemical Information and Modeling | DeepP450: Predicting Human P450 Activities of Small Molecules by Integrating Pretrained Protein Language Model and Molecular Representation

ABSTRACT: Cytochrome P450 enzymes (CYPs) play a crucial role in Phase I drug metabolism in the human body, and CYP activity toward compounds can significantly affect druggabil…

2024-4-08 1:00

Briefings in Bioinformatics | Protein-DNA binding sites prediction based on pre-trained protein language model and contrastive learning

ABSTRACT: Protein-DNA interaction is critical for life activities such as replication, transcription, and splicing. Identifying protein-DNA binding residues is essential for m…

2024-1-03 0:00